From a professional point of view, glucosamine can indeed alleviate pain in joints such as knees. But there are differences between individuals and injuries, so the specific effects will vary from person to person. As a student of medicine, I'll talk only about how chondroitin works and the people who use it. In particular, you can see if I am talking about whether you are in line with your actual situation. If you don't want to read these obscure words, you can only look at the bold font.
1. Component description
Each brand of chondroitin aminoglycose in the specific composition is still somewhat different, but the main ingredients are glucosamine and chondroitin, the two have repair work. In other words, glucosamine is a naturally synthesized substance in the human body, an important nutrient for chondrocyte formation, and a natural tissue component of healthy articular cartilage. Chondroitin is an important part of human connective tissue. These two substances can repair articular cartilage. Of course, that's the same sentence, which is theoretically possible, but the actual effect still needs to vary from person to person.
It has just been said that different brands will have their own different ingredients, and the proportion is slightly different. Some brands add their own patented ingredients to help, as in Move Free, where natural plant-derived fructose calcium borate, for example, soothes joints. Of course, other brands also have similar patent components.
Two. Function and principle
In this part, I will write the specific functions and principles of each component in theory, mainly glucosamine and chondroitin.
Glucosamine: repair, cleaning and Prevention
Exogenous glucosamine can stimulate cartilage cells to synthesize proteoglycan, supplement the missing components of cartilage matrix, thus promoting cartilage repair. This is why many brands of glucosamine chondroitin can be used to repair joint injuries.
Glucosamine can reduce the expression of IL-1B gene in chondrocytes by inhibiting a variety of inflammatory mediators, thereby reducing the inflammation-induced cartilage damage. It can inhibit harmful substances in the joint cavity and create a healthy environment for the joint.
Glucosamine can inhibit osteoclast differentiation through glycosylation. The formation of osteoclasts will lead to the reduction of bone, so preventing the increase of osteoclasts can prevent osteoporosis and alleviate cartilage degeneration.
Chondroitin: repair, care and resistance
Chondroitin can stimulate chondrocytes, promote the formation of new cartilage tissue, thus play a role in repairing damaged cartilage.
Because chondroitin has obvious soft bone, it can give priority to cartilage tissue and protect cartilage.
Like glucosamine, chondroitin can also inhibit the expression of pro-inflammatory genes, thereby reducing inflammation and achieving anti-inflammatory effect.
Generally speaking, chondroitin aminoglycoside has three functions: lubricating joints and maintaining joint function, strengthening cartilage structure, alleviating pain caused by arthritis and other discomfort symptoms.
Three. Suitable crowd
Health problems at knees and other joints are associated with age, joint strain, genetic factors, and obesity. Based on this, people who need to take glucosamine for proper use may have the following kinds:
Long term working crowd
People engaged in heavy manual labor for a long time
High intensity exercise crowd
Middle aged and elderly people
Bone degradation population
Joint pain or indisposition
Postoperative rehabilitation in Department of orthopedics